Constantin T, Foeldvari I, Vojinovic J, Horneff G, Burgos-Vargas R, Nikishina I, Akikusa JD, Avcin T, Chaitow J, Koskova E, Lauwerys BR, Calvo Penades I, Flato B, Gamir ML, Huppertz HI, Raad JJ, Jarosova K, Anton J, Macku M, Otero Escalante WJ, Rutkowska-Sak L, Trauzeddel R, Velez-Sanchez PJ, Wouters C, Wajdula J, Zang C, Bukowski J, Woodworth D, Vlahos B, Martini A, Ruperto N for Paediatric Rheumatology International Trials Organisation (PRINTO).
Two-year Efficacy and Safety of Etanercept in Pediatric Patients with Extended Oligoarthritis, Enthesitis-related Arthritis, or Psoriatic Arthritis.
J Rheumatol 2016;43:816-824.
Year: 2016 -

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Brunner HI, Ruperto N, Zuber Z, Keane C, Harari O, Kenwright A, Lu P, Cuttica R, Keltsev V, Xavier RM, Calvo I, Nikishina I, Rubio-Pérez N, Alexeeva E, Chasnyk V, Horneff G, Opoka-Winiarska V, Quartier P, Silva CA, Silverman E, Spindler A, Baildam E, Gámir ML, Martin A, Rietschel C, Siri D, Smolewska E, Lovell DJL, Martini A, De Benedetti F for the Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial.
Ann Rheum Dis 2015;74:1110-1117
Year: 2015 -

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Lovell DJ, Ruperto N, Mouy R, Paz E, Rubio-Pérez N, Silva CA, Abud-Mendoza C, Burgos-Vargas R, Gerloni V, Melo-Gomes JA, Saad-Magalhaes C, Chavez-Corrales J, Huemer C, Kivitz A, Blanco FJ, Foeldvari I, Hofer M, Huppertz HI, Deslandre CJ, Minden K, Punaro M, Block AJ, Giannini EH, Martini A for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Paediatric Rheumatology International Trials Organization (PRINTO).
Long-term safety, efficacy, and quality of life with intravenous abatacept in juvenile idiopathic arthritis: up to 7 years of treatment.
Arthritis Rheum 2015;67(10):2759-70.
Year: 2015 -

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De Benedetti F, Brunner H, Ruperto N, Schneider R, Xavier R, Allen R, Brown D, Chaitow J, Pardeo M, Espada G, Gerloni V, Myones B, Frane J, Wang J, Lipman TH, Bharucha KN, Martini A, Lovell D for the Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Catch-up growth during tocilizumab therapy for systemic juvenile idiopathic arthritis: Results from the TENDER trial.
Arthritis Rheum 2015;67(3):840-848.
Year: 2015 -

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Horneff G, Burgos-Vargas R, Constantin T, Foeldvari I, Vojinovic J, Chasnyk VG, Dehoorne J, Panaviene V, Susic G, Stanevica V, Kobusinska K, Zuber Z, Mouy R, Rumba-Rozenfelde I, Breda L, Dolezalova D, Job-Deslandre C, Wulffraat N, Alvarez D, Zang C, Wajdula J, Woodworth D, Vlahos B, Martini A, Ruperto N for the Paediatric Rheumatology International Trials Organisation (PRINTO)
Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study.
Ann Rheum Dis 2014;73:1114–1122
Year: 2014 -

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Rothmund F, Gerss J, Ruperto N, Däbritz J, Wittkowski H, Frosch M , Wulffraat NM, Wedderburn LR, Holzinger D, Gohar F, Vastert SJ, Brik R, Job Deslandre C, Melo-Gomes JA, Saad Magalhães C, Barcellona R, Russo R, Gattorno M, Martini A, Roth J, Foell D for the Paediatric Rheumatology International Trials Organization (PRINTO).
Validation of relapse risk biomarkers for routine use in patients with juvenile idiopathic arthritis.
Arthritis Care Res 2014;66(6):949-955
Year: 2014 -

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Ruperto N, Quartier P, Wulffraat N, Woo P, Ravelli A, Mouy R, Bader-Meunier B, Vastert SJ, Noseda E, D’Ambrosio D, Lecot J, Chakraborty A, Martini A, Chioato A for the Paediatric Rheumatology International Clinical Trials Organisation (PRINTO).
A phase II study to evaluate dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features.
Arthritis Rheum 2012;64(2):557-567
Year: 2012 -

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De Benedetti F, Brunner HI, Ruperto N, Kenwright A, Wright S, Calvo I, Cuttica R, Ravelli A, Schneider R, Woo P, Wouters C, Xavier R, Zemel L, Baildam E, Burgos-Vargas R, Dolezalova P, Garay SM, Merino R, Joos R, Grom A, Wulffraat N, Zuber Z, Zulian F, Lovell DJ, Martini A, for the Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis.
N Engl J Med 2012;367:2385-2395
Year: 2012 -

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Ruperto N, Brunner HI, Quartier P, Constantin T, Wulffraat N, Horneff G, Brik R, McCann L, Kasapcopur O, Rutkowska-Sak L, Schneider R, Berkun Y, Calvo I, Erguven M, Goffin L, Hofer M, Kallinich T, Oliveira SK, Uziel Y, Viola S, Nistala K, Wouters C, Cimaz R, Ferrandiz MA, Flato B, Gamir ML, Kone-Paut I, Grom A, Magnusson B, Ozen S, Sztajnbok F, Lheritier K, Abrams K, Kim D, Martini A, Lovell DJ for the Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis.
N Engl J Med 2012;367:2396-2406
Year: 2012 -

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Ruperto N, Lovell DJ, Li T, Sztajnbok F, Goldenstein-Schainberg C, Scheinberg M, Penades I, Fischbach M, Orozco J, Hashkes PJ, Hom C, Jung L, Lepore L, Oliveira S, Wallace C, Alessio M, Quartier P, Cortis E, Eberhard A, Simonini G, Lemelle I, Chalom E, Sigal LH, Block A, Covucci A, Nys M, Martini A, Giannini EH for the Paediatric Rheumatology INternational Trials Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Abatacept improves health-related quality of life, pain, sleep quality and daily participation in subjects with juvenile idiopathic arthritis.
Arthritis Care Res 2010;62:1542-1551
Year: 2010 -

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Visvanathan S, Wagner C, Marini JC, Lovell DJ, Martini A, Petty R, Cuttica R, Woo P, Espada G, Gattorno M, Apaz MT, Baildam E, Fasth A, Gerloni V, Lahdenne P, Quartier P, Saurenmann R, Travers S, Mendelsohn A, Xu S, Giannini EH , Ruperto N for the Paediatric Rheumatology INternational Trials Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
The effect of infliximab plus methotrexate on the modulation of inflammatory disease markers in juvenile idiopathic arthritis: analyses from a randomized, placebo-controlled trial.
Pediatr Rheumatol Online J. 2010;8:1-24
Year: 2010 -

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Ruperto N, Lovell DJ , Quartier P, Paz E, Rubio-Pérez N, Silva CA, Abud-Mendoza C, Burgos-Vargas R, Gerloni G, Melo-Gomes JA, Saad-Magalhães C, Chavez J, Huemer C, Kivitz A, Blanco FJ, Foeldvari I, Hofer M, Horneff G, Huppertz HI, Job Deslandre C, Loy A, Minden K, Punaro M, Flores Nunez A, Sigal LH, Block AJ, Nys M, Martini A, Giannini EH for the Paediatric Rheumatology INternational Trials Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Long-Term Safety and Efficacy of Abatacept in Children with Juvenile Idiopathic Arthritis.
Arthritis Rheum 2010;62(6):1792-1802
Year: 2010 -

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Ruperto N, Lovell DJ, Martini A, Giannini EH for the Paediatric Rheumatology International Trials Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG).
Performing trials in children with rheumatic diseases: comment on the editorial by Lehman.
Arthritis Rheum 2008; 58:1201–1202.
Year: 2008 -

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Ruperto N*, Lovell DJ*, Quartier P, Paz E, Rubio-Pérez N, Silva CA, Abud-Mendoza C, Burgos-Vargas R, Gerloni V, Melo-Gomes JA, Saad-Magalhães C, Sztajnbok F, Goldenstein-Schainberg C, Scheinberg M, Calvo Penades I, Fischbach M, Orozco J, Hashkes PJ, Hom C, Jung L, Lepore L, Oliveira S, Wallace C, Sigal LH, Block AJ, Covucci A, Martini A, Giannini EH, for the Paediatric Rheumatology INternational Trials Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG). *Both authors contributed equally to the paper.
Efficacy and safety of abatacept in children with juvenile idiopathic arthritis: a randomized, double-blind, placebo-controlled withdrawal trial.
Lancet 2008;372(9636):383-391
Year: 2008 -

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Lovell DJ*, Ruperto N*, Goodman S, Reiff A, Jung L, Jarosova K, Nemcova D, Mouy R, Sandborg C, Bohnsack J, Elewaut D, Foeldvari I, Gerloni V, Rovensky J, Minden K, Vehe RK, Wagner Weiner L, Horneff G, Huppertz HI, Olson NY, Medich JR, Carcereri-De-Prati R, McIlraith MJ, Giannini EH, Martini A, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Pediatric Rheumatology International Trials Organisation (PRINTO).
*Both authors contributed equally to the paper.
Adalimumab with or without methotrexate in juvenile rheumatoid arthritis.
N Engl J Med 2008;359:810-820
Year: 2008 -

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Lovell DJ, Ruperto N for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and the Pediatric Rheumatology International Trials Organisation (PRINTO).
Adalimumab in juvenile rheumatoid arthritis. The authors reply.
N Engl J Med 2008;359(23):2496-2497
Year: 2008 -

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Ruperto N, Lovell DJ, Cuttica R, Wilkinson N, Woo P, Espada G, Wouters C, Silverman ED, Balogh Z, Henrickson M, Apaz MT, Baildam E, Fasth A, Gerloni V, Lahdenne P, Prieur AM, Ravelli A, Saurenmann RK, Gamir ML, Wulffraat N, Marodi L, Petty RE, Joos R, Zulian F, McCurdy D, Myones BL, Nagy K, Reuman P, Szer I, Travers S, Beutler A, Keenan G, Clark J, Visvanathan S, Fasanmade A, Raychaudhuri A, Mendelsohn A, Martini A, Giannini EH; Paediatric Rheumatology International Trials Organisation; Pediatric Rheumatology Collaborative Study Group.
A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis.
Arthritis Rheum 2007 Aug 30;56(9):3096-3106
Year: 2007 -

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Ruperto N, Nikishina I, Pashanov ED, Shachbazian Y, Prieur AM, Mouy R, Joos R, Zulian F, Schwarz R, Artamonova V, Emminger W, Bandeira M, Buoncompagni A, Foeldvari I, Falcini F, Baildam E, Kone-Paut I, Alessio M, Gerloni V, Lenhardt A, Martini A, for the Paediatric Rheumatology International Trials Organization (PRINTO), Hanft G, Sigmund R, Simianer S.
A randomized, double-blind clinical trial of two doses of meloxicam compared with naproxen in children with juvenile idiopathic arthritis. Short- and long-term efficacy and safety results.
Arthritis Rheum 2005;52:563-572
Year: 2005 -

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